He is probably better known internationally for the song Senza Una Donna. He commenced his musical career within 1970 with his first only around 1976, and his foremost album inside 1983. His music, two around Italian & around English, is largely inspired by gospel, blues & rock, & replacement between syrupy ballads & further rythmic boogie-like pieces. He sang many duets, in public or even in disc, by owning Joe Cocker, Miles Davis, Paul Young, Sting, Luciano Pavarotti, and Johnny Hallyday.

European hit singles include Il Volo, Cosi Celeste, Baila (sexy tool), Diamante (featuring soul singer Randy Crawford) and Wonderful Globe (sustaining Eric Clapton). Zucchero's 2004 album ZU & Co, which features duets with among others Miles Davis, Paul Young, Sheryl Crow, The Cranberries's Dolores O'Riordan, B.B. King, John Lee Hooker, Brian May and Sting has sold millions of copies throughout Europe and the world.

Selected discography
Zucchero & a Randy Jackson Band (1985) Rispetto (1986) Blue's (1987) Snack bar Budapest original moving picture soundtrack (1988) Oro incenso & birra (1989) Zucchero sings his hits around English (1990) Zucchero (1991) Zucchero Survive at a Kremlin (1991) Miserere (1992) Diamante (1994) Spirito divino (1995) A right of Zucchero Sugar Fornaciari's greatest hits (1996) Bluesugar (1999) Overdose 500'amore a ballads (1999) Bluesugar & Whitechristmas (1999) Dislodge (2001) ZU & Co (2004) ZU & Co live at the Royal Albert Hall - may 6 2004 (2004) ZU & CO - American edition (2005) #84 US